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KMID : 0816120090120020171
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2009 Volume.12 No. 2 p.171 ~ p.176
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Hematologic Features of Children with Inflammatory Bowel Disease
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Kwon Chang-Gyu
Sun Yong-Han
Tchah Hann
Son Dong-Woo
Jeon In-Cheol
Nam Yoo-Nee
Ryoo Eell
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Abstract
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Purpose: The aim of this study was to evaluate hematologic features in Korean children with inflammatory bowel disease (IBD) in order to determine appropriate management strategies.
Methods: We retrospectively analyzed the complete blood count (CBC) profiles and assessed the incidence of anemia in 25 children with IBD (Crohn disease, 16; and ulcerative colitis, 9). The correlation between hemoglobin (Hb) and duration of illness and the activity index of IBD were also investigated.
Results: The incidence of anemia was 76% in IBD, 88% in Crohn disease, and 56% in ulcerative colitis. Leukocytosis and thrombocytosis were only found in Crohn disease (56% and 25%, respectively). No statistically significant correlation was observed between Hb and duration of illness in Crohn disease and ulcerative colitis or between Hb and the activity index in Crohn disease and ulcerative colitis.
Conclusion: The incidence of anemia found in this study was slightly higher than in previous reports. Additionally, there was no correlation between Hb and the duration of illness or the activity index. Therefore, even if the duration of illness is short, or the activity index is low, appropriate management of children with IBD should include careful evaluation for anemia.
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KEYWORD
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Inflammatory bowel disease, Crohn disease, Ulcerative colitis, Anemia, Complete blood cell count
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